Support Vector Machines (SVMs) are among the most important recent developments in pattern recognition and statistical machine learning. They have found a great range of applications in various fields including biology and medicine. However, biomedical researchers often experience difficulties grasping both the theory and applications of these important methods because of lack of technical background. The purpose of this book is to introduce SVMs and their extensions and allow biomedical researchers to understand and apply them in real-life research in a very easy manner. The book is to consist of two volumes: theory and methods (Volume 1) and cases studies (Volume 2).The proposed book follows the approach of “programmed learning” whereby material is presented in short sections called “frames”. Each frame consists of a very small amount of information to be learned, a multiple choice quiz, and answers to the quiz. The reader can proceed to the next frame only after verifying the correct answers to the current frame.