<DIV><I>You're on a placebo, Tristan. Least I've got an excuse. She told me: you're nothing, you're a control. This is all just you.<br/><br/></I><I>The Effect</I> is a clinical romance. Two young volunteers, Tristan and Connie, agree to take part in a clinical drug trial. Succumbing to the gravitational pull of attraction and love, however, Tristan and Connie manage to throw the trial off-course, much to the frustration of the clinicians involved. This funny, moving and perhaps surprisingly human play explores questions of sanity, neurology and the limits of medicine, alongside ideas of fate, loyalty and the inevitability of physical attraction.<br/><br/>Following on from the critical and commercial success of <I>Enron</I>, <I>The Effect</I> is the latest play from Lucy Prebble, and reunites <I>Enron</I>'s writer and director once more delivering a vibrant theatrical exploration into the human brain via the heart. This world premiere is co-produced by Headlong and will be performed at the National Theatre's Cottesloe Theatre from November 2012-23 February 2013, starring Billie Piper and Jonjo O'Neill. <br/><br/>The <I>Guardian</I> has selected <I>The Effect </I>as one of the highlights of 'the best theatre for autumn 2012' (2/9/12).</div>