<p><i> Cell Press Reviews: Stem Cells to Model and Treat Disease</i> provides in-depth and up-to-date reviews on the myriad ways that stem cells are being used to better understand and treat human disease. This publication offers essays from leaders in the stem cell field on some of the most important questions being faced in clinics and research labs, including the safety and efficacy of stem cell treatments, the use of stem cells to regenerate organs, the use of reprogrammed stem cells to model and treat disease, and the use of stem cells in clinical applications such as HIV disease and stroke. Contributors to this compilation include many prominent researchers in the field, such as: • Shinya Yamanaka, recipient, 2012 Nobel Prize in Physiology or Medicine; Professor, Center for iPS Cell Research and Application, Kyoto University and Gladstone Institute of Cardiovascular Disease, San Francisco, CA; President, International Society for Stem Cell Research • George Q. Daley, Director, Stem Cell Transplantation Program at Children’s Hospital Boston; Professor, Children’s Hospital Boston and Harvard Medical School • Irving Weissman, Director, Institute of Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine <i> Cell Press Reviews: Stem Cells to Model and Treat Disease</i> offers accessible and timely insights into the future promise and existing challenges of stem cell research. This publication is part of the <i>Cell Press Reviews</i> series, which brings together topical review articles recently published in Cell Press journals, including the <i>Trends in</i>… series. These compilations are curated by Cell Press journal editors and offer comprehensive updates from leaders in the field on the most cutting-edge and important scientific questions. </p><br><br>• Provides timely overviews on a wide range of stem cell applications<br>• Offers insight from experts on the key opportunities and challenges facing the field<br>• Features reviews on genetic, cellular, and molecular aspects of stem-cell-based applications<br>• Includes articles originally published in <i>Cell, Cell Stem Cell, Neuron, Trends in Molecular Medicine</i>, and <i>Trends in Biotechnology<br></i>