Released in 1990, <i>The Silence of the Lambs</i> is one of the defining films of recent American cinema. Adapted from the Thomas Harris novel and directed by Jonathan Demme, its central characters, Clarice Starling and Hannibal Lecter, have become contemporary icons. Jodie Foster is Starling, a rookie FBI agent on the trail of "Buffalo Bill," a serial killer who flays his victims. Anthony Hopkins is Lecter, the psychopathic former psychiatrist whom Starling consults about Bill's identity.<br> With its pairing of a perverse, invasive anti-hero and a questing, self-searching heroine, <i>The Silence of the Lambs</i> is a narrative of pursuit at several levels. In this study, Yvonne Tasker explores the way the film weaves together gothic, horror, and thriller conventions to generate both a distinctive variation on the cinematic portrayal of insanity and crime, and a fascinating intervention in the sexual politics of genre. She identifies the film as a key reference point for tracking the 90s obsession with police procedure and serial killing, analyzing its key themes of reason and madness, identity and belonging, aspiration and transformation.