<DIV>Heart disease is the leading cause of death in the UK and the United States. For those who survive heart disease, few victims recover completely. Cell therapies, tissue engineering, and biomaterials technologies have advanced and now offer the potential to reverse the damage caused by heart disease. Volume 1 of this important set provides comprehensive information on the pathology of heart disease and the cell therapies available. Opening chapters look at cardiac pathology and current therapies. Further chapters present gene and protein therapies for regeneration, cell therapies for cardiac regeneration, and clinical considerations of stem cell therapies.</div>