This book presents a spatially-based multiple methods approach to research serving academic and organizational researchers from across a wide variety of disciplines. For many, consideration of spatial relationships is an important component of their research questions, including those who may not have yet recognized GIS as a valuable tool. The book will provide readers essential steps to conceptualize and implement research and analysis, develop meaningful quantitative and qualitative geographic results and to communicate their findings using the visualization capabilities of GIS to assist decision-makers and affect policy. Furthermore it offers researchers a deeper understanding of social, economic and environmental questions considering spatial relationships in their data.The broad subject area of the project is the integration of spatial analysis as a research methodology. More specifically the book provides practical guidance for the identification, collection and analysis of appropriate research data for analysis in an Esri/ArcGIS context without being specific to a particular version of the software. The objective is to present ArcGIS with an eye towards incorporating spatial analysis as a fundamental component of mixed methods research. Because GIS is, by nature, an integrative technology which can draw together multiple data sources via a common spatial attribute, it is a natural fit for mixed-methods research. GIS provides the researcher an unparalleled ability to enhance their research incorporating a geographic perspective.