Manji, the immortal swordsman, lies imprisoned in the bakufu stronghold of the mysterious Habaki Kagemura. Seeking to impart the life-extending powers of the Manji's kessen chu bloodworms to other humans, Kagimura orders his medical examiners to discover the secrets of Manji's amazing regenerative abilities. Using a series of convicts as live subjects in an increasingly grisly series of twisted experiments, Burando, Kagimura's lead medical examiner, begins to grow more desperate and sickened with each horrifying failure. And through it all, Manji lives, and regenerates, and bides his time for the moment that he can pay back his tormentors... limb by limb!