This volume is an outgrowth of the international workshop entitled "Pseudo-Differential Operators: Complex Analysis and Partial Differential Equations" held at York University on August 4–8, 2008. It consists of the expository paper based on the 6-hour minicourse given by Professor Bert-Wolfgang Schulze, and sixteen papers based on lectures given at the workshop and on invitations. While the focus is on the current developments of pseudo-differential operators in the context of complex analysis and partial differential equations, other topics related to the analysis, applications and computations of pseudo-differential operators are featured.