Editor Tseng (cellular and molecular pharmacology, Rosalind Franklin U. of Medicine and Science) has collected professional opinions on the relationship between chronic dopamine depletion and cortico-subcortical dynamics in Parkinson's disease in this volume for fellow researchers and practitioners. Contributors discuss the latest unified models for Parkinson's that have been developed over the last 50 years, and they report on new physiological findings that involve phasic dopaminergic signaling, striatial dendritic adaptations and the diversity of up-stage voltage transitions. Computational analyses of the cortico-subcortical dynamics are also presented. Annotation ©2009 Book News, Inc., Portland, OR (booknews.com)