Designed as a bench resource, this includes step-by-step instructions for current technical approaches to post-transcriptional control. Contributors advise on bioinformatics approaches, methods applicable to fundamental issues in mRNA biology, and post-transcriptional control. Topics of the 21 articles include bioinformatics approaches for studying untranslated regions of mRNAs and post-transcriptional gene regulation, identification of mRNA polyadenylation sites in genomes, in-line probing analysis of riboswitches, targeted purification of RNA-specific ribonucleoproteins, advances in immuno-precipitation (RIP-Chip) analysis, RNA analysis by biosynthetic tagging, enrichment of alternatively splices isoforms, in vivo methods to assess polyadenylation efficiency, monitoring of temporal and spatial distribution of RNA in living yeast cells, analysis of RNA partitioning between the cytosol and endoplasmic reticulum compartments on mammalian cells, analysis of Poly(A) length effects, ribosome density mapping, identification of changes in gene expression, in vitro mRNA decay systems, synthetic precursor and inhibitor miRNAs, and a procedure that analyzes the efficiency of an siRNA. Annotation ©2008 Book News, Inc., Portland, OR (booknews.com)