Levy (medicine, Laboratory for Tumor and AIDS Virus Research and Cancer Research Institute, U. of California, San Francisco), who was one of the first to identify the AIDS virus, provides a volume for students, researchers, clinicians, and health care providers on HIV and AIDS. It covers features of AIDS pathogenesis, including aspects of HIV-1 and HIV-2 isolates involved; transmission and replication; the cells infected and consequences on tissues and organ systems; the host immune response; therapy; HIV infection and the development of cancer; and approaches to a vaccine for prevention. For this edition, new research is cited in each chapter, and discussion of the identification of genetic markers has been expanded. Other topics reflecting recent advances that have been expanded or are new include viral latency, innate immunity and prevention, and vaccine development. The reference section lists almost 5,000 sources. Annotation ©2007 Book News, Inc., Portland, OR (booknews.com)