<DIV>In <I>The Mangle of Practice</I> (1995), the renowned sociologist of science Andrew Pickering argued for a reconceptualization of research practice as a &ldquo;mangle,&rdquo; an open-ended, evolutionary, and performative interplay of human and non-human agency. While Pickering&rsquo;s ideas originated in science and technology studies, this collection aims to extend the mangle&rsquo;s reach by exploring its application across a wide range of fields including history, philosophy, sociology, geography, environmental studies, literary theory, biophysics, and software engineering.</P><P><I>The Mangle in Practice</I> opens with a fresh introduction to the mangle by Pickering. Several contributors then present empirical studies that demonstrate the mangle&rsquo;s applicability to topics as diverse as pig farming, Chinese medicine, economic theory, and domestic-violence policing. Other contributors offer examples of the mangle in action: real-world practices that implement a self-consciously &ldquo;mangle-ish&rdquo; stance in environmental management and software development. Further essays discuss the mangle as philosophy and social theory. As Pickering argues in the preface, the mangle points to a shift in interpretive sensibilities that makes visible a world of de-centered becoming. This volume demonstrates the viability, coherence, and promise of such a shift, not only in science and technology studies, but in the social sciences and humanities more generally.</P><P><I>Contributors</I>: Lisa Asplen, Dawn Coppin, Adrian Franklin, Keith Guzik, Casper Bruun Jensen,Yiannis Koutalos, Brian Marick, Randi Markussen, Andrew Pickering, Volker Scheid, Esther-Mirjam Sent, Carol Steiner, Maxim Waldstein</div>