Biochemists and microbiologists from around the world examine a very thoroughly studied organism in light of new insight into gene sequences and the network of interacting genes and proteins that result in the life processes. They focus on B. subtilis and its closest relatives, but incorporate comparative analyses of pathways and mechanisms used in other gram-positive bacteria as well as in E. coli ; combine whole genome analysis and biochemical genetics to provide a broad picture of macromolecular synthesis, metabolic pathways, developmental process, and adaptive responses; and present as much of the information as possible in graphical or tabular format. Annotation c. Book News, Inc., Portland, OR (booknews.com)