Researchers in pediatric hematology offer a collection of molecular techniques for the diagnosis, classification, and treatment of childhood hematological disorders. Each protocol is described in step- by-step detail, including the principle behind the method, required equipment, reagents, and known pitfalls. Methods include diagnosis of Fanconi anemia, dyskeratosis congenita, immunodeficiency, and most forms of hemoglobinopathy. In addition, the book details molecular human platelet antigen genotyping, a PCR procedure for thrombophilia screening, and methods for detecting residual leukemia below the threshold of light microscopy. The volume's 16 chapters are edited by Goulden and Steward, both of the Royal Hospital for Children in Bristol, UK. Annotation (c) Book News, Inc., Portland, OR (booknews.com)