Police across Tamaulipas, Mexico's north-eastern state are hunting Chano Salgado. A reclusive young widower and political apostate, Salgado goes on the run after he is persuaded to blow up the pipelines of a sluicing operation sucking the local groundwater dry. Meanwhile, Evan Hatch, a London-based flack for an "issues-management" PR firm, is dying from leukemia. Hoping to find a donor, he tracks down his long-lost brother in Mexico (from where he had been adopted at birth) while en route to the WTO meeting in Seattle. Chano, desperately needing to cross the border, finds his brother (Evan) first, and steals his passport. In the third narrative strand, Chano's young son, Daniel, himself given up for adoption in Costa Rica, is also looking for his father. Traveling to Mexico, he is forced to flee when the police take him hostage hoping to force his father to turn himself in. Squirreling himself away on a freighter, he is rescued by a UK refugee organization whose activists fly to Seattle with him to participate in the protest hoping to reunite him with his father, who, masquerading as Evan, is about to give a speech to the European Roundtable of Industrialists.