This issue of Clinics in Chest Medicine, guest edited by Robert Kotloff, focuses on the topics of Lung Transplantation. Articles include: Candidate Selection, Timing of Listing, and Choice of Procedure for Lung Transplantation; Lung Allocation in the United States, Selection and Management of the Lung Donor; Novel Approaches to Expanding the Lung Donor Pool: Donation After Cardiac Death and Ex Vivo Conditioning; Extracorporeal Life Support as a Bridge to Lung Transplantation; Survival and Quality of Life of Patients Undergoing Lung Transplant; Primary Graft Dysfunction; Acute Allograft Rejection: Cellular and Humoral Processes, and more!