Voit (Georgia Institute of Technology) presents a textbook for a graduate or advanced undergraduate course in a young discipline that analyzes biological phenomena as actions of complex systems. He begins with the fundamentals of modeling and features of the molecular inventories that bring biological systems to life. Then he discusses case studies from some of the frontiers in systems biology and synthetic biology. Among the topics are static network models, the mathematics of biological systems, protein systems, physiological modeling with the heart as an example, and systems biology in medicine and drug development. Garland Science is an imprint of Taylor & Francis Group. Annotation ©2012 Book News, Inc., Portland, OR (booknews.com)