When an old gangster friend of Leo's father makes a request he "can't refuse," Leo and his band of drunks, delve into the world of environmental politics in search of Caroline Nobel, a spoiled brat, without the sense God gave a gopher. With the help of "the Boys"—a group of aging winos who are his modern day "Baker Street Irregulars"—Leo fights Native American tribal politics, industrial pollution, and psychotic grannies to fulfill his obligation to a friend.