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Electroporation-Based Therapies for Cancer

Electroporation-based therapies for cancer looks at electroporation-based therapies for cancer. Cancer kills about one American per minute, amounting to over 500,000 deaths in the US and millions, worldwide, each year.<br><br>There is a critical need for safe, effective, and affordable alternative treatment modalities, especially for inoperable, recurring and chemo-resistant cancers, that do not respond well to current treatment regimen. Electrical-pulse-mediated, enhanced drug delivery technique, known as electroporation is one of the ways to effectively treat these patients. Towards this end, this book provides a comprehensive overview of electroporation-based clinical studies in the hospitals for various cancer treatments including melanomas, head and neck cancers, chest wall breast carcinomas and colorectal cancers and research studies in the lab using cell lines, primary cells, and animals. This technique is especially suitable for low and middle-income countries, where due to lack of infrastructure and resources, many cancers are diagnosed at late stages and this safe, effective, economical, out-patient-based and quick (it only takes a few minutes to treat a tumor) technique is a boon to these patients for palliative and other care with enhanced quality of life. From basics to clinical medical applications of electroporation are discussed by interdisciplinary authors including practicing oncological surgeons, medical professional, and academic and other researchers.<ul><li>Provides novel and recent clinical applications of electrochemotherapy for various cancers, including melanomas, sarcomas, superficial extreme melanoma, chest wall breast carcinoma, and colorectal cancers</li><li>Extensive study of a number of cell lines, including human breast cancer, lung cancer, cervical cancer, leukemia, and mouse breast cancer using both reversible and irreversible electroporation techniques</li><li>In vitro study of delivery of various commonly prescribed/administered breast cancer chemo and hormone drugs, such as Doxorubicin, Paclitaxel, Bleomycin, and Tamoxifen</li></ul>
 

  Autore: Sundararajan Raji (EDT)  
  Editore: Woodhead Pub Ltd  
  Isbn: 1907568158  
  EAN : 9781907568152  
  Data pub. 25 Jul 14  
  Collana: Woodhead Pub Ltd (Hardcover)  
  Classificazione:MEDICAL  
  Pagine: 306  
  Prezzo: € 170,00  







 
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