<p><i>Arthritis Research: Methods and Protocols, Second Edition </i>expands upon the<i> </i>first edition to present new and current techniques for the research of arthritis and related conditions. A compendium of leaders in the field contribute chapters that cover practical research methods such as the intravital multiphoton microscopy technique, techniques for evaluating exhausted CD8 T cell and for studying nucleic acid sensors and their effects, methods for <i>in vivo</i> tetracycline-controlled transgenic mice and T cell receptor transgenic mice, protocols to detect V(D)J recombination products and microRNA, and the technique to make bleomycin-induced dermal fibrosis. Written in the successful <i>Methods in Molecular Biology</i> series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.</p><p> </p><p>Authoritative and easily accessible, <i>Arthritis Research: Methods and Protocols, Second Edition </i>will serve both professionals and novices with state-of-the-art techniques pertaining to this fascinating research field.</p>