Editors Boehm-Davis, Durso, and Lee present this APA publication regarding human systems integration (HSI) in a tiered structure. Part one, section one defines HSI discussing the emergence of the discipline, early applications in the military, and other case studies. Section two presents perspectives on HSI as a systems development issue. Part two details factors affecting HSI performance at the levels of bodily physiology including muscular fatigue and sleep needs, perceptual and cognitive function, and organizational and economic systems. Part three extends those considerations to the design of effective systems in sections addressing user interface, personnel management, and organizational structure. Annotation ©2015 Ringgold, Inc., Portland, OR (protoview.com)