The Western Pacific Region is home to 26% of the world’s population but 36% of the world’s tobacco users. The Regional Committee endorsed the Regional Action Plan for the Tobacco Free Initiative in the Western Pacific (2015–2019) at its sixty-fifth session in October 2014. Building on our experiences, the new regional action plan is structured around three pillars: strengthening sustainable institutional capacity; developing comprehensive legislation and regulation; and facilitating consistent enforcement through a whole-of-society approach. For each of these strategic outcomes, the regional action plan identifies clear objectives and critical steps to be taken by countries and WHO.