This guide is developed to assist TB and HIV program managers and other stakeholders in monitoring and evaluation for collaborative TB/HIV activities. It is intended to facilitate collection of standardized data and to help in interpretation and dissemination of these data for program improvement at the national and subnational level. It also aims to ensure consistency of data systems across all the agencies and stakeholders involved in HIV, TB and collaborative TB /HIV activities and avoid duplication of efforts by providing a set of internationally accepted and standardized indicators for monitoring and evaluation of program performance.