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Epigenetic Cancer Therapy

<p><i>Epigenetic Cancer Therapy</i> unites issues central to a translational audience actively seeking to understand the topic. It is ideal for cancer specialists, including oncologists and clinicians, but also provides valuable information for researchers, academics, students, governments, and decision-makers in the healthcare sector. </p><p>The text covers the basic background of the epigenome, aberrant epigenetics, and its potential as a target for cancer therapy, and includes individual chapters on the state of epigenome knowledge in specific cancers (including lung, breast, prostate, liver).</p><p>The book encompasses both large-scale intergovernmental initiatives as well as recent findings across cancer stem cells, rational drug design, clinical trials, and chemopreventative strategies. As a whole, the work articulates and raises the profile of epigenetics as a therapeutic option in the future management of cancer.</p><ul><li>Concisely summarizes the therapeutic implications of recent, large-scale epigenome studies, including the cancer epigenome atlas</li><li>Discusses targeted isoform specific versus pan-specific inhibitors, a rational drug design approach to epigenetics relevant to pharmacoepigenetic clinical applications</li><li>Covers new findings in the interplay between cancer stem cells (CSCs) and drug resistance, demonstrating that epigenetic machinery is a candidate target for the eradication of these CSCs</li></ul>
 

  Autore: Gray Steven (EDT)  
  Editore: Elsevier Science Ltd  
  Isbn: 0128002069  
  EAN : 9780128002063  
  Data pub. 16 Jul 15  
  Collana: Elsevier Science Ltd (Hardcover)  
  Classificazione:MEDICAL  
  Pagine: 748  
  Prezzo: € 122,30  







 
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