<div>There are many different ways to treat complex chronic middle ear disease,<p>with ongoing advancements being made globally. Diverse approaches are</p><p>necessitated for variations in patient age, degree of infection, extent</p><p>of middle ear remodeling, inflammation severity, and underlying</p><p>mechanisms of Eustachian tube dysfunction. Addressing multinational and</p><p>clinical nuances, the editors have compiled 48 chapters with eclectic</p><p>perspectives from otology experts in 13 countries.<br><br>The</p><p>surgical anatomy of the middle ear cleft and mastoid and underlying</p><p>pathophysiological mechanisms of chronic otitis media are clinically</p><p>challenging. Articles cover anatomy, physiology, disease</p><p>characterizations and manifestations, clinical evaluation, office</p><p>management, surgical procedures, and new horizons. Traditional and</p><p>newer hybrid techniques for systematic disease and inflammatory</p><p>conditions are presented in roundtable format, for example, underlay</p><p>fascia tympanoplasty as well as the use of cartilage and bioengineered</p><p>materials.<br><br>Selected Key Topics:<br></p><ul><li>Applied middle ear anatomy and physiology</li><li>Pathologic mechanisms of chronic otitis media </li><li>Office evaluation, management and surgical decision making</li><li>Mastoid cavity obliteration and canal wall reconstruction</li><li>Challenges in tympanoplasty and ossicular chain reconstruction</li><li>Traditional and hybrid tympanomastoid surgery</li><li>Hearing implants in the chronic ear</li></ul>This<p>is an exceptional teaching tool for ear surgeons in training as well as</p><p>a must-have clinical resource for practicing otolaryngologists.<br></p></div>